The translation of stem-cell research to the clinic includes critical issues such as reproducibility and quality assurance of cell lines. Currently, the ‘practice’ of stem cell production remains highly idiosyncratic and requires specific craft like skills.
Here we propose the utilization of sonification methods, which is the use of nonspeech audio to convey or contextualize complex information. Sonification has been used to elucidate scientific information, for example from earthquakes, solar radiation. In this project, for the first time sonification will be utilized to measure the performance of stem-cell production which is captured by our novel software - ProtocolNavigator. Our assumption is based on the fact that human auditory system is highly sensitive to recognize and ‘feel’ a good musical performance. Additionally from other studies it is evident that, sonification can inform on the sources of process loss, determination of critical steps, and most importantly provide an assessment method for process improvement.